Search | Engineering

Subscribe Submit

Home Journals Focus Achievement Fronts About Us 中文版

Resource Type

Journal Article 254

Year

2023 30

2022 27

2021 17

2020 18

2019 10

2018 10

2017 23

2016 12

2015 11

2014 6

2013 9

2012 7

2011 16

2010 8

2009 6

2008 7

2007 5

2006 2

2005 5

2004 1

open ︾

Keywords

supply chain 5

supply chain management 4

Full-duplex 3

blockchain 3

Anammox 2

Bacterial community 2

Bayesian inference 2

COVID-19 2

China 2

Full adder 2

coordination 2

development roadmap 2

disruptive technology 2

full scale test 2

green development 2

high-quality development 2

industrial chain 2

intelligent manufacturing 2

resilience 2

open ︾

Search scope:

排序： Display mode:

Analysis and Prospect of the Pharmaceutical Industry Development Trend in China

Kong Fei, Cao Yuan, Xu Ming, Li Haiyan, Qiao Jie

Strategic Study of CAE 2023, Volume 25, Issue 5, Pages 1-10 doi: 10.15302/J-SSCAE-2023.05.003

Abstract: the pharmaceutical industry in five aspects: precision, safety, timeliness, affordability, and policy guaranteeresearch and development, improving multi-level medical security channels, and enhance the fullchain of policy protection and the implementation efficiency, thus to provide a reference for subsequent

Keywords： pharmaceutical industry pharmaceutical research and development priority strategies drivers fullchain guarantee

HTML PDF Collect

FULL TIME-SPACE GOVERNANCE STRATEGY AND TECHNOLOGY FOR CROPLAND NON-POINT POLLUTION CONTROL IN CHINA

Frontiers of Agricultural Science and Engineering 2023, Volume 10, Issue 4, Pages 593-606 doi: 10.15302/J-FASE-2023522

Abstract: In this review, a proposal is made for a full time-space governance strategy that prioritizes sourceThe 4R chain technology system is specifically reviewed, including source reduction, process retentionThe 4R chain technology system with the full time-space governance strategy was applied at the scale

Keywords： 4R chain technology system agricultural non-point source pollution case study full time-space governance

HTML PDF Collect

Reliability guarantee framework for the Sichuan–Tibet Railway

Frontiers of Engineering Management 2021, Volume 8, Issue 4, Pages 480-491 doi: 10.1007/s42524-021-0170-4

Abstract: This study proposes a novel reliability framework to guarantee the ideal operation state of the Sichuan–Tibet

Keywords： Sichuan–Tibet Railway operational efficiency reliability guarantee Nine-Connotation implementation

HTML PDF Collect

Prevention and Control of Waste Plastics Pollution in China

Wang Qi, Qu Jinping, Shi Bi, Chen Ning, Nie Min, Yang Shuangqiao

Strategic Study of CAE 2021, Volume 23, Issue 1, Pages 160-166 doi: 10.15302/J-SSCAE-2021.01.020

Abstract:

Prevention and control of waste plastics is an important component of the national strategy in China. In this study, the sources as well as the current situation and measures for recycling of waste plastics in China were comprehensively analyzed. We proposed an all-rounded tactic for the prevention and control of plastic pollution in China based on the life-cycle assessment of plastics. Technically, waste plastic pollution should be prevented and controlled throughout the entire process covering plastic synthesis, processing, utilization, and recycling; specifically, it includes reduction of waste plastics from the origin by developing new degradable raw materials and their environmentally friendly alternatives, design and processing of high-performance plastic products with extended service life, development of new technologies offering efficient and large-scale capacity for recycling waste plastics, as well as safe disposal of the ultimate plastic wastes. At the government level, policy guidance must be strengthened, and administrative supervision be implemented. At the enterprise level, an effective recycling system should be instituted to clarify recycling responsibilities of producers, sellers, and consumers, providing policy and technical suggestions for the prevention and control of waste plastics. At the public level, citizens’ environmental awareness must be aroused to promote a nationwide participation in waste management. These suggestions are favorable to a more green and sustainable development of China’s plastic industry and even national economy.

Keywords： waste plastic environmental pollution prevention and control recycle full-chain management

HTML PDF Collect

Investigating the raveling test for full-depth reclamation

Robert HILL, Andrew BRAHAM

Frontiers of Structural and Civil Engineering 2018, Volume 12, Issue 2, Pages 222-226 doi: 10.1007/s11709-017-0423-9

Abstract: Full-Depth Reclamation (FDR) is a sustainable method of building pavement structure compared to more

Keywords： raveling full depth reclamation

HTML PDF Collect

CAR T cells redirected against tumor-specific antigen glycoforms: can low-sugar antigens guarantee a

Frontiers of Medicine 2022, Volume 16, Issue 3, Pages 322-338 doi: 10.1007/s11684-021-0901-2

Abstract: Immune-based therapies have experienced a pronounced breakthrough in the past decades as they acquired multiple US Food and Drug Administration (FDA) approvals for various indications. To date, six chimeric antigen receptor T cell (CAR-T) therapies have been permitted for the treatment of certain patients with relapsed/refractory hematologic malignancies. However, several clinical trials of solid tumor CAR-T therapies were prematurely terminated, or they reported life-threatening treatment-related damages to healthy tissues. The simultaneous expression of target antigens by healthy organs and tumor cells is partly responsible for such toxicities. Alongside targeting tumor-specific antigens, targeting the aberrantly glycosylated glycoforms of tumor-associated antigens can also minimize the off-tumor effects of CAR-T therapies. Tn, T, and sialyl-Tn antigens have been reported to be involved in tumor progression and metastasis, and their expression results from the dysregulation of a series of glycosyltransferases and the endoplasmic reticulum protein chaperone, Cosmc. Moreover, these glycoforms have been associated with various types of cancers, including prostate, breast, colon, gastric, and lung cancers. Here, we discuss how underglycosylated antigens emerge and then detail the latest advances in the development of CAR-T-based immunotherapies that target some of such antigens.

Keywords： cancer immunotherapy chimeric antigen receptor solid tumors tumor-associated antigen glycosylation O-glycans adoptive cell therapy

HTML PDF Collect

Service Security of Underwater Tunnel Lining Structures and Corresponding Guarantee Countermeasures

He Chuan,Liu Sijin,Zhang Yuchun and Feng Kun

Strategic Study of CAE 2017, Volume 19, Issue 6, Pages 44-51 doi: 10.15302/J-SSCAE-2017.06.007

Abstract:

This paper analyzes four aspects of the safety problems in tunnel lining structures: design and construction, environmental erosion, sudden natural disasters, and sudden accidents. A survey of underwater tunneling such as the Huangpu River’s cross-river tunnel and the underground traffic tunnel in Shanghai was carried out, and the status quo of China’s underwater tunnel lining structure was analyzed. Based on these analyses, countermeasures guaranteeing the long-life security of underwater tunnel structures are being sought regarding tunnel construction, structural performance degradation, sudden natural disasters, and sudden accidents. These countermeasures are being sought to effectively protect and ensure the service performance of the tunnel structures during their entire life cycle. These security measures can ensure the safe performance of the structure during its entire life cycle, even under long service times. This research can serve as a reference for enhancing the structural security of underwater tunnels and other major tunnel structures.

Keywords： underwater tunnels service security security guarantee countermeasures long life structural defects

HTML PDF Collect

Partial anammox achieved in full scale biofilm process for typical domestic wastewater treatment

Frontiers of Environmental Science & Engineering 2022, Volume 16, Issue 3, doi: 10.1007/s11783-021-1467-6

Abstract:

• A full scale biofilm process was developed for typical domestic wastewater

Keywords： Full scale Anammox Domestic wastewater Biofilm Candidatus Brocadia

HTML PDF Collect

Safety Guarantee Measures for Subsea Shield Tunnel Segments Based on Life Cycle Deterioration Analysis

Liu Sijin,He Chuan,Sun Qi and Feng Kun

Strategic Study of CAE 2017, Volume 19, Issue 6, Pages 52-60 doi: 10.15302/J-SSCAE-2017.06.008

Abstract:

The segment joint is the weak link in the lining structure of subsea tunnels, as it is under the continuous coupled effect of high water pressure and the corrosive seawater environment. If its performance deteriorates, it will seriously affect the safety of the lining structure of entire subsea shield tunnels. Based on an analysis of existing research into segment joint erosion and deterioration, a tunnel service time factor is introduced. Considering the influence of seawater pressure infiltration and chloride ion erosion and migration, a model analyzing the erosion and deterioration of the segment joint over its whole life cycle was subsequently established. The law governing the progressive erosion and deterioration of the segment joints of subsea tunnels over the entire life cycle was analyzed. The effects of seawater pressure and ion concentration on the erosion, deterioration, and steel corrosion of segment joints were studied. Based on the analysis of erosion and deterioration over the entire life cycle, economic and rational measures to ensure the long-term safety of the segment lining structure of subsea shield tunnels were proposed.

Keywords： shield tunnel safety guarantee deterioration analysis ion erosion segment joint

HTML PDF Collect

Pricing and production strategies in remanufacturing from the perspectives of supply chain: Review and

Frontiers of Engineering Management doi: 10.1007/s42524-023-0251-7

Abstract: literature on pricing and production strategies in remanufacturing from four perspectives of supply chain, namely, government policy, consumer characteristics, relationships among firms, and supply chain structures

Keywords： remanufacturing reverse and closed-loop supply chain circular economy

HTML PDF Collect

Genetic Crop Improvement: A Guarantee for Sustainable Agricultural Production

Jianmin Wan

Engineering 2018, Volume 4, Issue 4, Pages 431-432 doi: 10.1016/j.eng.2018.07.019

HTML PDF Collect

Novel sensing techniques for full-scale testing of civil structures

Kaoshan DAI, Zhenhua HUANG

Frontiers of Structural and Civil Engineering 2012, Volume 6, Issue 3, Pages 240-256 doi: 10.1007/s11709-012-0172-8

Abstract: Performing full-scale structural testing is an important methodology for researchers and engineers inFull scale testing helps the researchers understand civil infrastructures’ loading scenarios, behaviorsTo conduct a full-scale structural testing, sensors are used for data acquisitions.and select the most effective sensors, this study reviewed and categorized new sensing techniques for full-scaleThe detailed descriptions of wireless sensors and remote sensing techniques and their on-site full-scale

Keywords： sensing technique full-scale testing wireless sensor remote sensing LiDAR laser vibrometer

HTML PDF Collect

Modeling of the resilient supply chain system from a perspective of production design changes

Frontiers of Engineering Management Pages 96-106 doi: 10.1007/s42524-022-0235-z

Abstract: Building an effective resilient supply chain system (RSCS) is critical and necessary to reduce the riskof supply chain disruptions in unexpected scenarios such as COVID-19 pandemic and trade wars.To overcome the impact of insufficient raw material supply on the supply chain in mass disruption scenariosof the change impact process is presented to evaluate the resilience of both the product and supply chain

Keywords： resilient supply chain supply chain disruption domain modeling product design changes

HTML PDF Collect

Digitalization for supply chain resilience and robustness: The roles of collaboration and formal contracts

Frontiers of Engineering Management Pages 5-19 doi: 10.1007/s42524-022-0229-x

Abstract: Results show that digitalization has a direct effect on supply chain resilience, and supply chain collaborationbetween digitalization and supply chain robustness.as an organizational factor in managing supply chain disruptions.but weaken the relationship between supply chain collaboration and supply chain resilience.collaboration and provides insights into governing supply chain partners’ behavior.

Keywords： digitalization supply chain resilience robustness collaboration formal contract

HTML PDF Collect

Disruptive technologies for advancing supply chain resilience

Frontiers of Engineering Management 2023, Volume 10, Issue 2, Pages 360-366 doi: 10.1007/s42524-023-0257-1

Abstract: Disruptive technologies provide a new paradigm for supply chain risk management and bring opportunitiesand challenges for the improvement of supply chain resilience (SCRes).The results show that disruptive technologies can provide the supply chain with flexibility, visibility

Keywords： supply chain resilience disruptive technology supply chain risk